U-Blot® eIF2α mouse mAb

Name: U-Blot® eIF2α mouse mAb
SKU: WM0729
Availability: InStock

$268.00

Size:50μL

SKU: WM0729-50

Catalog No.: WM0729

Specification: 50μL/100μL

Stock: In stock

U-Blot® eIF2α mouse mAb Learn more

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Background：The translation initiation factor EIF2 catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits. Binding occurs as a ternary complex of methionyl-tRNA, EIF2, and GTP. EIF2 is composed of 3 nonidentical subunits, the 36-kD EIF2-alpha subunit (EIF2S1), the 38-kD EIF2-beta subunit (EIF2S2; MIM 603908), and the 52-kD EIF2-gamma subunit (EIF2S3; MIM 300161). The rate of formation of the ternary complex is modulated by the phosphorylation state of EIF2-alpha (Ernst et al., 1987 [PubMed 2948954]).[supplied by OMIM, Feb 2010],

Product Overview

Catalog No.: WM0729
SKU: WM0729-50
Category: Mouse mAbs
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: eIF2α
Reactivity: Human,Mouse,Rat
Application: WB,IF,IP
MW(Calculated): --
MW(Observed): 38kD
Host Species: Mouse
Isotype: --
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: WB 1:1000;ICC 1:200;IF 1:50-200
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: --
Clonality: Monoclonal
Clone No.: --
Immunogen: Purified recombinant human eIF2α protein fragments expressed in E.coli.
Sequence: --
Specificity: This antibody detects endogenous levels of eIF2α and does not cross-react with related proteins.
Gene Name: eif2s1
Protein Name: --
Other Name: Dmel\CG6376;Dmel_CG6376;drosE2F1;E;Sev-CycE;3A;E;var;3-93E;E2-promoter binding facto;E2F 1;E2F transcription factor 1;E2F-1;E2f-PA;E2f-PB;E2f-PC;E2F1;E2f1 E2F transcription factor 1;E2F1_HUMAN;Evar;3;164;KIAA4009;l;3;07172;l;3;j3B1;l;3;j3C2;l;3;rM729;mKIAA4009;OTTHUMP00000030661;PBR3;PRB binding protein E2F 1;PRB-binding protein E2F-1;RBAP 1;RBAP-1;RBAP1;RBBP-3;RBBP3;RBP 3;RBP3;Retinoblastoma-associated protein 1;Retinoblastoma-binding protein 3;Transcription factor E2F1.
Organism-1: Human
Gene ID-1: 1965
SwissProt-1: P05198
Organism-2: Mouse
Gene ID-2: --
SwissProt-2: Q6ZWX6
Organism-3: --
Gene ID-3: --
SwissProt-3: --
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Cytoplasm, Stress granule . Colocalizes with NANOS3 in the stress granules. .