U-Blot® SIRT1 Monoclonal Antibody

U-Blot® SIRT1 Monoclonal Antibody
U-Blot® SIRT1 Monoclonal Antibody
$9,999.00
Size:200µg
SKU: WM2982-200

Catalog No.: WM2982

Specification: 200µg/10µg

Stock: In stock

Product details, specifications, documents, and related products are available from the catalog record. Learn more

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Product information

Product detailsSpecificationsQ & AEducation

Background:SIRT1 ( Sirtuin 1 , SIR2L1 ) is a member of the Sirtuin family of proteins related to the yeast Sir2 protein. Like Sir2 and other Sirtuins, SIRT1 is an NAD-dependent histone and protein deacetylase. SIRT1 catalyzes the removal of acetyl groups from a variety of protein substrates ( NBS1 , p53 , Ku70, etc. ) as well as from Histone H4 Lys16 . SIRT1 is involved in the regulation of a number of cellular processes, including transcription, metabolism, DNA repair and aging, and increased SIRT1 is associated with extended lifespan of C. elegans .

Product Overview

Catalog No.
WM2982
SKU
WM2982-200
Category
Mouse mAbs
Product Type
Other
Size
200µg/10µg
Stock Status
In stock
Available Stock
999
Minimum Order Quantity
1

Storage & Compliance

Research Use Only
Yes

Additional Specifications

Target
--
Reactivity
Human
Applications
ChIP; WB; IP; IF; ICC
MW(Calculated)
120 kDa
Host Species
Mouse
Isotype
IgG1
Recommended Dilution Ratio
Applications Validated by Active Motif: WB: 0.5 - 2.0 µg/ml dilution The addition of 0.05% Tween 20 in the blocking buffer and primary antibody incubation buffer is recommended to aid in detection by Western blot. Individual optimization may be required.
Formulation
10 mM sodium phosphate pH 7.5, 150 mM NaCl, 30% glycerol, 0.035% sodium azide.
Purification
Protein G Chromatography
Storage
Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
Concentration
--
Clonality
Monoclonal
Clone Number
2G1/F7
Immunogen
This SIRT1 antibody was raised against a synthetic peptide corresponding to amino acids 581-630 of human SIRT1.
Specificity
--
Gene Name
--
Other Name
Sirtuin 1, SIR2L1
Gene ID
--
Cellular Localization
--
Function
--

Tech Support

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Documents

Datasheet, COA, SDS, and protocol files can be requested from technical support.

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Keywords:Mouse mAbs