U-Blot® FADD (phospho S194) Rabbit mAb

U-Blot® FADD (phospho S194) Rabbit mAb
U-Blot® FADD (phospho S194) Rabbit mAb
$288.00
Size:100μl
SKU: WT9052-100

Catalog No.: WT9052

Specification: 100μL/300μL

Stock: In stock

Product details, specifications, documents, and related products are available from the catalog record. Learn more

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Product information

Product detailsSpecificationsQ & AEducation

Background：The protein is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals. Through its C-terminal death domain, this protein can be recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, and TNFSF10/TRAIL-receptor, and thus it participates in the death signaling initiated by these receptors. Interaction of this protein with the receptors unmasks the N-terminal effector domain of this protein, which allows it to recruit caspase-8, and thereby activate the cysteine protease cascade.

Product Overview

Catalog No.
WT9052
SKU
WT9052-100
Category
Phosphorylation
Product Type
Other
Size
100μL/300μL
Stock Status
In stock
Available Stock
20
Minimum Order Quantity
1

Storage & Compliance

Storage
Store at -20°C. Avoid repeated freeze-thaw cycles
Research Use Only
Yes

Additional Specifications

Antibody Type
Recombinant monoclonal
Target
Phospho-FADD (Ser194)
Reactivity
Human
Application
WB
MW(Calculated)
23kDa
MW(Observed)
23kDa
Host Species
Rabbit
Isotype
IgG
Conjugate
Unconjugated
Modification
Phosphorylation
Modification Site
Ser194
Recommended dilution ratio
WB 1:500-2000
Composition
PBS, Glycerol, BSA
Purification process
Protein A
storageCondition
Store at -20°C. Avoid repeated freeze-thaw cycles
Stability
Stable for 12 months from date of receipt / reconstitution.
Concentration
--
Clonal
Recombinant monoclonal
Clone Number
W-R27
Immunogen
polypeptide
Gene Name
FADD
Protein Name
Fas-associated death domain protein
Alternative name
MORT1
Organism-1
Human
Gene ID
8772
SwissProt-1
Q13158
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Background：
Background
The protein is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals. Through its C-terminal death domain, this protein can be recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, and TNFSF10/TRAIL-receptor, and thus it participates in the death signaling initiated by these receptors. Interaction of this protein with the receptors unmasks the N-terminal effector domain of this protein, which allows it to recruit caspase-8, and thereby activate the cysteine protease cascade.
Cellular Localization
Cytosol, Membrane
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Background：The protein is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals. Through its C-terminal death domain, this protein can be recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, and TNFSF10/TRAIL-receptor, and thus it participates in the death signaling initiated by these receptors. Interaction of this protein with the receptors unmasks the N-terminal effector domain of this protein, which allows it to recruit caspase-8, and thereby activate the cysteine protease cascade.
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Tech Support

ucallm

01

Documents

Datasheet, COA, SDS, and protocol files can be requested from technical support.

02

Storage & Handling

Storage
Store at -20°C. Avoid repeated freeze-thaw cycles
06

Contact Support

Emailinfo@mail.ucallm.com

Phone+(1)-866-986-9598

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Keywords:Phosphorylation