- Antibody Type
- Recombinant monoclonal
- Target
- Phospho-S6 Ribosomal Protein (Ser235/Ser236)
- Reactivity
- Human
- Application
- WB,ICC/IF
- MW(Calculated)
- 32kDa
- MW(Observed)
- 32kDa
- Host Species
- Mouse
- Isotype
- Ig2B/Kappa
- Conjugate
- Unconjugated
- Modification
- Phosphorylation
- Modification Site
- --
- Recommended dilution ratio
- WB 1:500-1000;ICC/IF 1:50
- Composition
- PBS, Glycerol, BSA
- Purification process
- Protein G
- storageCondition
- Store at -20°C. Avoid repeated freeze-thaw cycles
- Stability
- Stable for 12 months from date of receipt / reconstitution.
- Concentration
- --
- Clonal
- Recombinant monoclonal
- Clone Number
- W-R28
- Immunogen
- polypeptide
- Gene Name
- RPS6
- Protein Name
- 40S ribosomal protein S6
- Alternative name
- --
- Organism-1
- Human
- Gene ID
- 6194
- SwissProt-1
- P62753
- --
- Background:
- Background
- Ribosomal protein S6 (rpS6 or eS6) is a component of the 40S ribosomal subunit and is therefore involved in translation. Mouse model studies have shown that phosphorylation of eS6 is involved in the regulation of cell size, cell proliferation, and glucose homeostasis. Important S6 ribosomal protein phosphorylation sites include several residues (Ser235, Ser236, Ser240, and Ser244) located within a small, carboxy-terminal region of the S6 protein.
- Cellular Localization
- Cytosol, Endoplasmic reticulum, Nucleus
- --
- Background:Ribosomal protein S6 (rpS6 or eS6) is a component of the 40S ribosomal subunit and is therefore involved in translation. Mouse model studies have shown that phosphorylation of eS6 is involved in the regulation of cell size, cell proliferation, and glucose homeostasis. Important S6 ribosomal protein phosphorylation sites include several residues (Ser235, Ser236, Ser240, and Ser244) located within a small, carboxy-terminal region of the S6 protein.
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