- Antibody Type
- Recombinant monoclonal
- Target
- Phospho-AKT1 (Ser473)
- Reactivity
- Human, Rat
- Application
- WB
- MW(Calculated)
- 56 kDa
- MW(Observed)
- 56-60 kDa
- Host Species
- Rabbit
- Isotype
- IgG
- Conjugate
- Unconjugated
- Modification
- Phosphorylation
- Modification Site
- Ser473
- Recommended dilution ratio
- WB 1:1000-1:2000
- Composition
- PBS, Glycerol, BSA
- Purification process
- Protein A affinity purification
- storageCondition
- Store at -20°C. Avoid repeated freeze-thaw cycles
- Stability
- Stable for 12 months from date of receipt / reconstitution.
- Concentration
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- Clonal
- Recombinant monoclonal
- Clone Number
- W-R33
- Immunogen
- polypeptide
- Gene Name
- AKT1
- Protein Name
- RAC-alpha serine/threonine-protein kinase
- Alternative name
- AKT1, PKBα, Protein kinase B alpha
- Organism-1
- Human
- Gene ID
- 207
- SwissProt-1
- P31749
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- Background:
- Background
- AKT1 is one of 3 closely related serine/threonine-protein kinases (AKT1, AKT2 and AKT3) called the AKT kinase, which regulate many processes including metabolism, proliferation, cell survival, growth and angiogenesis. AKT has an important role in the regulation of NF-kappa-B-dependent gene transcription and positively regulates the activity of CREB1 (cyclic AMP (cAMP)-response element binding protein).
- Cellular Localization
- Nucleus, Cell membrane, Cytoplasm
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- Background:AKT1 is one of 3 closely related serine/threonine-protein kinases (AKT1, AKT2 and AKT3) called the AKT kinase, which regulate many processes including metabolism, proliferation, cell survival, growth and angiogenesis. AKT has an important role in the regulation of NF-kappa-B-dependent gene transcription and positively regulates the activity of CREB1 (cyclic AMP (cAMP)-response element binding protein).
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