
Sku: WT9610A-C55-8

Catalog No.: WT9067
Specification: 100μL/300μL
Stock: In stock
Product details, specifications, documents, and related products are available from the catalog record. Learn more
Background:Plays a role in neuronal development and polarity, as well as in axon growth and guidance, neuronal growth cone collapse and cell migration. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. May play a role in endocytosis. Phosphorylation at Thr-514 by GSK3B abolishes tubulin-binding leading to destabilization of microtubule assembly in axons and neurodegeneration
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