U-Blot® Phospho-HDAC1 (Ser406) Mouse mAb

U-Blot® Phospho-HDAC1 (Ser406) Mouse mAb
U-Blot® Phospho-HDAC1 (Ser406) Mouse mAb
$288.00
Size:100μl
SKU: WT9072-100

Catalog No.: WT9072

Specification: 100μL/300μL

Stock: In stock

Product details, specifications, documents, and related products are available from the catalog record. Learn more

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Product information

Product detailsSpecificationsQ & AEducation

Background：Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Aurora kinases phosphorylate HDAC1 at Ser406 during prophase, immediately after cells begin mitosis, resulting in reduced deacetylase activity of HDAC1. This modification plays an essential role in regulating cell cycle progression, as well as controlling the expression of genes involved in central nervous system development.

Product Overview

Catalog No.
WT9072
SKU
WT9072-100
Category
Phosphorylation
Product Type
Other
Size
100μL/300μL
Stock Status
In stock
Available Stock
20
Minimum Order Quantity
1

Storage & Compliance

Storage
Store at -20°C. Avoid repeated freeze-thaw cycles
Research Use Only
Yes

Additional Specifications

Antibody Type
Recombinant monoclonal
Target
Phospho-HDAC1 (Ser406)
Reactivity
Human
Application
WB
MW(Calculated)
55 kDa
MW(Observed)
60 kDa
Host Species
Mouse
Isotype
IgG2b/Kappa
Conjugate
Unconjugated
Modification
Phosphorylation
Modification Site
Ser406
Recommended dilution ratio
WB 1:1000
Composition
PBS, Glycerol, BSA
Purification process
Protein G
storageCondition
Store at -20°C. Avoid repeated freeze-thaw cycles
Stability
Stable for 12 months from date of receipt / reconstitution.
Concentration
--
Clonal
Recombinant monoclonal
Clone Number
W-R46
Immunogen
polypeptide
Gene Name
HDAC1
Protein Name
Histone deacetylase 1
Alternative name
Phospho-HDAC1 (Ser406)
Organism-1
Human
Gene ID
3067
SwissProt-1
Q13547
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Background：
Background
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Aurora kinases phosphorylate HDAC1 at Ser406 during prophase, immediately after cells begin mitosis, resulting in reduced deacetylase activity of HDAC1. This modification plays an essential role in regulating cell cycle progression, as well as controlling the expression of genes involved in central nervous system development.
Cellular Localization
Nucleus
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Background：Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Aurora kinases phosphorylate HDAC1 at Ser406 during prophase, immediately after cells begin mitosis, resulting in reduced deacetylase activity of HDAC1. This modification plays an essential role in regulating cell cycle progression, as well as controlling the expression of genes involved in central nervous system development.
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Tech Support

ucallm

01

Documents

Datasheet, COA, SDS, and protocol files can be requested from technical support.

02

Storage & Handling

Storage
Store at -20°C. Avoid repeated freeze-thaw cycles
06

Contact Support

Emailinfo@mail.ucallm.com

Phone+(1)-866-986-9598

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Keywords:Phosphorylation