U-Blot® Phospho-PTP1B (Ser352) Rabbit pAb

U-Blot® Phospho-PTP1B (Ser352) Rabbit pAb
U-Blot® Phospho-PTP1B (Ser352) Rabbit pAb
$288.00
Size:100μl
SKU: WT9090-100

Catalog No.: WT9090

Specification: 100μL/300μL

Stock: In stock

Product details, specifications, documents, and related products are available from the catalog record. Learn more

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Product information

Product detailsSpecificationsQ & AEducation

Background：PTP1B is a tyrosine-protein phosphatase which acts as a regulator of endoplasmic reticulum unfolded protein response and mediates dephosphorylation of EIF2AK3/PERK; inactivating the protein kinase activity of EIF2AK3/PERK. During metaphase, PTP1B is phosphorylated by protein kinase C (PKC) at S352, which is also phosphorylated in response to osmotic stress, but do not markedly change PTP1B activity.

Product Overview

Catalog No.
WT9090
SKU
WT9090-100
Category
Phosphorylation
Product Type
Other
Size
100μL/300μL
Stock Status
In stock
Available Stock
20
Minimum Order Quantity
1

Storage & Compliance

Storage
Store at -20°C. Avoid repeated freeze-thaw cycles
Research Use Only
Yes

Additional Specifications

Antibody Type
Polyclonal
Target
Phospho-PTP1B (Ser352)
Reactivity
Human
Application
WB
MW(Calculated)
50 kDa
MW(Observed)
50 kDa
Host Species
Rabbit
Isotype
IgG
Conjugate
Unconjugated
Modification
Phosphorylation
Modification Site
Ser352
Recommended dilution ratio
WB 1:1000-1:2000
Composition
PBS, Glycerol, BSA
Purification process
Protein A affinity purification
storageCondition
Store at -20°C. Avoid repeated freeze-thaw cycles
Stability
Stable for 12 months from date of receipt / reconstitution.
Concentration
--
Clonal
Polyclonal
Clone Number
--
Immunogen
polypeptide
Gene Name
PTPN1
Protein Name
Protein tyrosine phosphatase 1B
Alternative name
PTPN1
Organism-1
Human
Gene ID
5770
SwissProt-1
P18031
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Background：
Background
PTP1B is a tyrosine-protein phosphatase which acts as a regulator of endoplasmic reticulum unfolded protein response and mediates dephosphorylation of EIF2AK3/PERK; inactivating the protein kinase activity of EIF2AK3/PERK. During metaphase, PTP1B is phosphorylated by protein kinase C (PKC) at S352, which is also phosphorylated in response to osmotic stress, but do not markedly change PTP1B activity.
Cellular Localization
Endoplasmic reticulum membrane
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Background：PTP1B is a tyrosine-protein phosphatase which acts as a regulator of endoplasmic reticulum unfolded protein response and mediates dephosphorylation of EIF2AK3/PERK; inactivating the protein kinase activity of EIF2AK3/PERK. During metaphase, PTP1B is phosphorylated by protein kinase C (PKC) at S352, which is also phosphorylated in response to osmotic stress, but do not markedly change PTP1B activity.
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Tech Support

ucallm

01

Documents

Datasheet, COA, SDS, and protocol files can be requested from technical support.

02

Storage & Handling

Storage
Store at -20°C. Avoid repeated freeze-thaw cycles
06

Contact Support

Emailinfo@mail.ucallm.com

Phone+(1)-866-986-9598

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Keywords:Phosphorylation