U-Blot® Phospho-Tau (Ser199) Rabbit mAb

U-Blot® Phospho-Tau (Ser199) Rabbit mAb
U-Blot® Phospho-Tau (Ser199) Rabbit mAb
$288.00
Size:100μl
SKU: WT9103-100

Catalog No.: WT9103

Specification: 100μL/300μL

Stock: In stock

Product details, specifications, documents, and related products are available from the catalog record. Learn more

Product information

Background:Promotes microtubule assembly and stability and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.

Product Overview

Catalog No.
WT9103
SKU
WT9103-100
Category
Phosphorylation
Product Type
Other
Size
100μL/300μL
Stock Status
In stock
Available Stock
20
Minimum Order Quantity
1

Storage & Compliance

Storage
Store at -20°C. Avoid repeated freeze-thaw cycles
Research Use Only
Yes

Additional Specifications

Antibody Type
Recombinant monoclonal
Target
Phospho-Tau (Ser199)
Reactivity
Human, Mouse, Rat
Application
WB, IHC-P, ICC/IF, FC
MW(Calculated)
79 kDa
MW(Observed)
55 kDa
Host Species
Rabbit
Isotype
IgG
Conjugate
Unconjugated
Modification
Phosphorylation
Modification Site
Ser199
Recommended dilution ratio
WB 1:1000-1:3000; IHC-P 1:200-1:1000; ICC/IF 1:50; FC 1:50-1:100
Composition
PBS, Glycerol, BSA
Purification process
Protein A affinity purification
storageCondition
Store at -20°C. Avoid repeated freeze-thaw cycles
Stability
Stable for 12 months from date of receipt / reconstitution.
Concentration
--
Clonal
Recombinant monoclonal
Clone Number
W-R73
Immunogen
polypeptide
Gene Name
MAPT
Protein Name
Microtubule-associated protein Tau
Alternative name
MAPT, MAPTL, MTBT1
Organism-1
Human
Gene ID
4137
SwissProt-1
P10636
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Background:
Background
Promotes microtubule assembly and stability and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.
Cellular Localization
Membrane, Cytoplasm, Cytoskeleton, Microtubule
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Background:Promotes microtubule assembly and stability and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.
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Tech Support

ucallm

01

Documents

Datasheet, COA, SDS, and protocol files can be requested from technical support.

02

Storage & Handling

Storage
Store at -20°C. Avoid repeated freeze-thaw cycles
06

Contact Support

Emailinfo@mail.ucallm.com

Phone+(1)-866-986-9598

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Keywords:Phosphorylation