- Antibody Type
- Polyclonal
- Target
- Phospho-Serine
- Reactivity
- Species Independent
- Application
- ELISA,WB,IHC,IP
- MW(Calculated)
- Multiple
- MW(Observed)
- Multiple
- Host Species
- Rabbit
- Isotype
- IgG
- Conjugate
- Unconjugated
- Modification
- Serine phosphorylation
- Modification Site
- --
- Recommended dilution ratio
- ELISA 1:250; WB 1:250; IP 10 µg/mg crude protein; IHC 1:50
- Composition
- 250ug/mL antibody stored in PBS, 50% glycerol
- Purification process
- Affinity purified with serine-phosphorylated peptide immobilized on agarose
- storageCondition
- Product is stable for several weeks at 4°C. For extended storage, store product at –20ºC.
- Stability
- Stable for 12 months from date of receipt / reconstitution.
- Concentration
- --
- Clonal
- Polyclonal
- Clone Number
- --
- Immunogen
- Affinity purified with serine-phosphorylated peptide immobilized on agarose
- Gene Name
- --
- Protein Name
- --
- Alternative name
- --
- Organism-1
- --
- Gene ID
- --
- SwissProt-1
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- --
- Background:
- Background
- Serine phosphorylation is one of the most prevalent and reversible post-translational modifications in eukaryotic proteins. Catalyzed by kinases and reversed by phosphatases, this modification covalently attaches a phosphate group to the hydroxyl group of serine residues. It alters protein charge, conformation and intermolecular interactions, acting as a core molecular switch to regulate cell cycle, signal transduction, proliferation, differentiation, metabolism and immune response. Dysregulated serine phosphorylation is implicated in inflammation, cancer and multiple human diseases.
- Cellular Localization
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- --
- Background:Serine phosphorylation is one of the most prevalent and reversible post-translational modifications in eukaryotic proteins. Catalyzed by kinases and reversed by phosphatases, this modification covalently attaches a phosphate group to the hydroxyl group of serine residues. It alters protein charge, conformation and intermolecular interactions, acting as a core molecular switch to regulate cell cycle, signal transduction, proliferation, differentiation, metabolism and immune response. Dysregulated serine phosphorylation is implicated in inflammation, cancer and multiple human diseases.
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