Recombinant Human pro-NGF/pro-Beta-NGF Protein

Recombinant Human pro-NGF/pro-Beta-NGF Protein
Recombinant Human pro-NGF/pro-Beta-NGF Protein
$140.00
Size:10μg
SKU: PR00046-10μg

Catalog No.: PR00046

Specification: 10μg/50μg/500μg/1mg

Stock: In stock

Product details, specifications, documents, and related products are available from the catalog record. Learn more

Product information

Background:The precursor form of the nerve growth factor (proNGF) like its mature form is characterized by the cystin knot motif consisting of three cystine bridges, whereas proneurotrophins and mature neurotrophins elicit opposite biological effects. ProNGF functions preferentially via the complex of pan-neurotrophin receptor p75 (p75NTR) and vps10p domain-containing receptor sortilin inducing neuronal apoptosis and contributing to age- and disease-related neurodegeneration.

Product Overview

Catalog No.
PR00046
SKU
PR00046-10μg
Category
Neurotrophic Factors
Product Type
Other
Size
10μg/50μg/500μg/1mg
Stock Status
In stock
Available Stock
20
Minimum Order Quantity
1

Storage & Compliance

Research Use Only
Yes

Additional Specifications

Molecule
pro-NGF/pro-Beta-NGF
Background
The precursor form of the nerve growth factor (proNGF) like its mature form is characterized by the cystin knot motif consisting of three cystine bridges, whereas proneurotrophins and mature neurotrophins elicit opposite biological effects. ProNGF functions preferentially via the complex of pan-neurotrophin receptor p75 (p75NTR) and vps10p domain-containing receptor sortilin inducing neuronal apoptosis and contributing to age- and disease-related neurodegeneration.
Species
Human
Source
E. coli
Tags
Tag free
Accession
P01138
KnownAs
Beta-Nerve Growth Factor; Beta-NGF; NGF; NGFB;β-NGF; pro-Beta NGF
Protein Length
Glu19-Ala241
Predicted Molecular Mass
25 KDa
N-terminal Sequence
--
SDS-PAGE
30 KDa, reducing conditions
Endotoxin
<1 EU/µg as determined by LAL test.
Concentration
--
Purity-SDS-PAGE
--
Purity-SEC-HPLC
--
Activity
--
Form
Lyophilized
Formulation
Lyophilized from a 0.2 μm filtered solution of 20mM Histidine-HCl,5%Sucrose,0.02%Tween80,pH5.0.
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below.
Storage
Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. Please minimize freeze-thaw cycles and use a manual defrost freezer.
Reconstitution
Reconstitute the lyophilized protein in sterile water at a concentration of greater than 100 µg/mL.

Tech Support

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Documents

Datasheet, COA, SDS, and protocol files can be requested from technical support.

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Keywords:Neurotrophic Factors