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Engineered Exosome Platform

Natural exosomes possess favorable biocompatibility, low immunogenicity and innate cell-targeting capacity, making them novel biological delivery carriers. Nevertheless, the abundance of functional cargo in native exosomes is limited, and exosomes from different sources exhibit heterogeneity in molecular composition and biological effects.

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RVG Lipid-Achor Kit-A Tool for Neural-Targeted Exosome Engineering

The RVG (Rabies Virus Glycoprotein) peptide is a 29‑amino‑acid targeting peptide derived from the rabies virus glycoprotein.

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Exosome-Mediated Cell Communication

As critical carriers for intercellular information transfer, exosomes are released into the extracellular space.

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Exosome Biogenesis & Molecular Composition

Exosomes are mainly generated via the canonical endosomal pathway, starting with plasma membrane endocytosis. First, the plasma membrane invaginates to form early endosomes.

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Exosome Research Workflow

A comprehensive technical system covering sample preparation, EV isolation, multi-dimensional characterization, cargo analysis, functional validation and mechanistic dissection has been established around the biogenesis, isolation, characterization, molecular composition and biological functions of extracellular vesicles (EVs).

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Exosome-Based Biomarkers

Extracellular vesicles (EVs) are widely present in various biological fluids including blood, urine, saliva and cerebrospinal fluid.

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MSC-Derived EVs for Tissue Repair & Regeneration

Mesenchymal stem cell-derived extracellular vesicles (MSC-EVs) constitute a key component of the paracrine effects of MSCs.

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Immunology & Inflammation

Extracellular vesicles (EVs) serve as vital mediators for intercellular communication within the immune system.

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Cancer Biology & Therapeutics

Tumor-derived Exosomes (TDEs) are critical extracellular vesicles secreted by tumor cells, which play key regulatory roles in tumor initiation, progression and therapeutic response.

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