U-Blot® Synuclein-α Rabbit mAb

U-Blot® Synuclein-α Rabbit mAb
U-Blot® Synuclein-α Rabbit mAb
$268.00
Size:50μL
SKU: WR4587-50

Catalog No.: WR4587

Specification: 50μL/100μL

Stock: In stock

U-Blot® Synuclein-α Rabbit mAb Learn more

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Product information

Product detailsSpecificationsQ & AEducation

Background：Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Alternatively spliced transcripts encoding different isoforms have been identified for this gene. [provided by RefSeq, Feb 2016],

Product Overview

Catalog No.
WR4587
SKU
WR4587-50
Category
Rabbit mAbs
Product Type
Other
Size
50μL/100μL
Stock Status
In stock
Available Stock
20
Minimum Order Quantity
1

Storage & Compliance

Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only
Yes

Additional Specifications

Target
Synuclein-α
Reactivity
Human,Mouse,Rat,C.elegans
Application
WB,IHC,IF,IP,ELISA
MW(Calculated)
14kD
MW(Observed)
18kD
Host Species
Rabbit
Isotype
IgG,Kappa
Conjugate/Modification
Unmodified
Modification site
--
Recommended Dilution Ratio
IHC 1:200-1:1000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
Form
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Source
--
Purification
Protein A
Purity
--
storageCondition
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
--
Clonality
Monoclonal
Clone No.
PT0854R
Immunogen
--
Sequence
--
Specificity
Endogenous
Gene Name
SNCA
Protein Name
Alpha-synuclein
Other Name
SNCA;NACP;PARK1;Alpha-synuclein;Non-A beta component of AD amyloid;Non-A4 component of amyloid precursor;NACP
Organism-1
Human
Gene ID-1
6622
SwissProt-1
P37840
Organism-2
Mouse
Gene ID-2
20617
SwissProt-2
O55042
Organism-3
Rat
Gene ID-3
29219
SwissProt-3
P37377
Organism-4
--
gene ID-4
--
SwissProt-4
--
Cellular Localization
Cytoplasm . Membrane . Nucleus . Cell junction, synapse . Secreted . Cell projection, axon . Membrane-bound in dopaminergic neurons (PubMed:15282274). Expressed and colocalized with SEPTIN4 in dopaminergic axon terminals, especially at the varicosities (By similarity). .

Tech Support

ucallm

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Documents

Datasheet, COA, SDS, and protocol files can be requested from technical support.

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Storage & Handling

Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
06

Contact Support

Emailinfo@ucallmlabs.com

Phone+(1)-866-986-9598

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Keywords:Rabbit mAbs