U-Blot® IGF1R (Phospho Tyr1135/1136)/Insulin Receptor β (Phospho Tyr1150/1151) Rabbit mAb

U-Blot® IGF1R (Phospho Tyr1135/1136)/Insulin Receptor β (Phospho Tyr1150/1151) Rabbit mAb
U-Blot® IGF1R (Phospho Tyr1135/1136)/Insulin Receptor β (Phospho Tyr1150/1151) Rabbit mAb
$288.00
Size:50μL
SKU: WR4597-50

Catalog No.: WR4597

Specification: 50μL/100μL

Stock: In stock

U-Blot® IGF1R (Phospho Tyr1135/1136)/Insulin Receptor β (Phospho Tyr1150/1151) Rabbit mAb Learn more

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Product information

Product detailsSpecificationsQ & AEducation

Background：This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014],

Product Overview

Catalog No.
WR4597
SKU
WR4597-50
Category
Rabbit mAbs
Product Type
Other
Size
50μL/100μL
Stock Status
In stock
Available Stock
20
Minimum Order Quantity
1

Storage & Compliance

Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only
Yes

Additional Specifications

Target
IGF IR
Reactivity
Human,Mouse,Rat
Application
WB,IF,ELISA
MW(Calculated)
156kD
MW(Observed)
95kD
Host Species
Rabbit
Isotype
IgG,Kappa
Conjugate/Modification
Phospho
Modification site
--
Recommended Dilution Ratio
WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;
Form
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Source
--
Purification
Protein A
Purity
--
storageCondition
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
--
Clonality
Monoclonal
Clone No.
PT0867R
Immunogen
--
Sequence
--
Specificity
Antibody detects endogenous levels of IGF-I receptor and insulin receptor only when phosphorylated at tyrosine 1135/1136 or tyrosine 1150/1151, respectively. The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites): MAyLN
Gene Name
IGF1R
Protein Name
Insulin-like growth factor 1 receptor
Other Name
IGF1R;Insulin-like growth factor 1 receptor;Insulin-like growth factor I receptor;IGF-I receptor;CD antigen CD221;INSR;Insulin receptor;IR;CD antigen CD220
Organism-1
Human
Gene ID-1
3480;3643
SwissProt-1
P06213;P08069
Organism-2
Mouse
Gene ID-2
16001;16337
SwissProt-2
--
Organism-3
Rat
Gene ID-3
25718
SwissProt-3
P24062;P15127
Organism-4
--
gene ID-4
--
SwissProt-4
--
Cellular Localization
Cell membrane ; Single-pass type I membrane protein .

Tech Support

ucallm

01

Documents

Datasheet, COA, SDS, and protocol files can be requested from technical support.

02

Storage & Handling

Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
06

Contact Support

Emailinfo@ucallmlabs.com

Phone+(1)-866-986-9598

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HoursMonday-Friday 09:00-18:00 CST

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Keywords:Rabbit mAbs