U-Blot® SOX-2 Rabbit mAb

U-Blot® SOX-2 Rabbit mAb
U-Blot® SOX-2 Rabbit mAb
$268.00
Size:50μL
SKU: WR4811-50

Catalog No.: WR4811

Specification: 50μL/100μL

Stock: In stock

U-Blot® SOX-2 Rabbit mAb Learn more

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Product information

Product detailsSpecificationsQ & AEducation

Background：SRY-box 2(SOX2) Homo sapiens This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT). [provided by RefSeq, Jul 2008],

Product Overview

Catalog No.
WR4811
SKU
WR4811-50
Category
Rabbit mAbs
Product Type
Other
Size
50μL/100μL
Stock Status
In stock
Available Stock
20
Minimum Order Quantity
1

Storage & Compliance

Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only
Yes

Additional Specifications

Target
SOX-2
Reactivity
Human,Mouse,Rat
Application
WB,IHC,IF,IP,ELISA
MW(Calculated)
34kD
MW(Observed)
34kD
Host Species
Rabbit
Isotype
IgG,Kappa
Conjugate/Modification
Tyr416
Modification site
--
Recommended Dilution Ratio
IHC 1:1000-1:4000;WB 1:1000-1:20000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
Form
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Source
--
Purification
Protein A
Purity
--
storageCondition
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
--
Clonality
Monoclonal
Clone No.
PT0870R
Immunogen
--
Sequence
--
Specificity
Endogenous
Gene Name
SOX2
Protein Name
Transcription factor SOX-2
Other Name
SOX2;Transcription factor SOX-2
Organism-1
Human
Gene ID-1
6657
SwissProt-1
P48431
Organism-2
Mouse
Gene ID-2
20674
SwissProt-2
P48432
Organism-3
--
Gene ID-3
--
SwissProt-3
--
Organism-4
--
gene ID-4
--
SwissProt-4
--
Cellular Localization
Nucleus speckle . Cytoplasm . Nucleus . Acetylation contributes to its nuclear localization and deacetylation by HDAC3 induces a cytoplasmic delocalization (By similarity). Colocalizes in the nucleus with ZNF208 isoform KRAB-O and tyrosine hydroxylase (TH) (By similarity). Colocalizes with SOX6 in speckles. Colocalizes with CAML in the nucleus (By similarity). Nuclear import is facilitated by XPO4, a protein that usually acts as a nuclear export signal receptor (By similarity). .

Tech Support

ucallm

01

Documents

Datasheet, COA, SDS, and protocol files can be requested from technical support.

02

Storage & Handling

Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
06

Contact Support

Emailinfo@ucallmlabs.com

Phone+(1)-866-986-9598

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Keywords:Rabbit mAbs