U-Blot® Histone H3 (Acetyl Lys56) Rabbit mAb

U-Blot® Histone H3 (Acetyl Lys56) Rabbit mAb
U-Blot® Histone H3 (Acetyl Lys56) Rabbit mAb
$700.00
Size:100μL
SKU: WT8208-100

Catalog No.: WT8208

Specification: 100μL/300μL

Stock: In stock

Product details, specifications, documents, and related products are available from the catalog record. Learn more

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Product information

Product detailsSpecificationsQ & AEducation

Background: Histone H3 forms tetramers with H4 to build chromatin skeleton. Its N-tail and core lysine residues undergo reversible acetylation regulated by HAT and HDAC. Acetylation neutralizes positive charge, relaxes chromatin and recruits bromodomain co-activators. Different acetyl sites on H3 separately control transcription, DNA repair, cell cycle and replication. H3K56ac lies inside nucleosome core, catalyzed by Rtt109/TIP60. It regulates chromatin assembly after DNA replication and DNA double-strand break repair. Loss of H3K56ac causes genome instability and cell cycle arrest.

Product Overview

Catalog No.
WT8208
SKU
WT8208-100
Category
Histone Modification Antibodies
Product Type
Other
Size
100μL/300μL
Stock Status
In stock
Available Stock
20
Minimum Order Quantity
1

Storage & Compliance

Storage
-20.0°C
Research Use Only
Yes

Additional Specifications

Target
Acetylated Histone H3 Lysine 56 (K56ac)
Reactivity
Human Vertebrates
Application
WB, ICC, IHC, ELISA, Luminex
MW(Calculated)
15kD
MW(Observed)
--
Host Species
Rabbit
Isotype
Rabbit IgG
Conjugate
Unconjugated
Modification
Acetyl
Modification site
Lys56
Recommended dilution ratio
WB 1 ug/mL - 2 ug/mL; ICC 0.5 ug/mL - 2 ug/mL; IHC 1 ug/mL – 10 ug/mL; ELISA 0.5 ug/mL - 1 ug/mL; Luminex 0.5 ug/mL – 2 ug/mL.
Formulation
50% Glycerol/PBS with 1% BSA and 0.09% sodium azide
Source
--
Purification
Protein A affinity purified from an animal origin-free culture supernatant
Purity
--
Storage
-20.0°C
Concentration
1 mg/mL
Clonality
Recombinant Monoclonal
Clone Number
WR-133
Immunogen
An acetyl-peptide corresponding to the Acetyl-Histone H3 (Lys56).
Sequence
--
Specificity
This antibody reacts to Histone H3 acetylated at Lysine 56 (K56ac). No cross reactivity with other acetylated Lysines in histone H3.
Gene name
--
Protein name
--
Alternative name
H3K56ac
Organism-1
Human
Gene ID‑1
8350;8351;8352;8353;8354;8355;8356;8357;8358;8970
SwissProt-1
P68433
Organism-2
Mouse
Gene ID‑2
319152;15077;15078
SwissProt-2
P68433
Organism-3
Rat
Gene ID‑3
291159;100361558
SwissProt-3
Q6LED0;P84245
Organism-4
--
Gene ID‑4
--
SwissProt-4
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Cellular Localization
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Tech Support

ucallm

01

Documents

Datasheet, COA, SDS, and protocol files can be requested from technical support.

02

Storage & Handling

Storage
-20.0°C
03

Contact Support

Emailinfo@mail.ucallm.com

Phone+(1)-866-986-9598

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Keywords:Histone Modification Antibodies