U-Blot® Histone H3 (Phospho Thr6) Rabbit mAb

U-Blot® Histone H3 (Phospho Thr6) Rabbit mAb
U-Blot® Histone H3 (Phospho Thr6) Rabbit mAb
$700.00
Size:100μL
SKU: WT8465-100

Catalog No.: WT8465

Specification: 100μL/300μL

Stock: In stock

Product details, specifications, documents, and related products are available from the catalog record. Learn more

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Product information

Product detailsSpecificationsQ & AEducation

Background: Histone threonine phosphorylation is a reversible modification regulated by kinases and phosphatases. Phosphorylation changes chromatin charge, recruits effector proteins to coordinate cell cycle progression, mitosis and DNA damage response, each threonine site carries unique functions. H3T6 phosphorylation (H3pT6) is catalyzed by cell cycle-related kinases, highly induced during mitosis. It loosens condensed mitotic chromatin and mediates spindle protein recruitment for chromosome segregation. This mark also accumulates at DNA double-strand break sites to activate repair signaling.

Product Overview

Catalog No.
WT8465
SKU
WT8465-100
Category
Histone Modification Antibodies
Product Type
Other
Size
100μL/300μL
Stock Status
In stock
Available Stock
20
Minimum Order Quantity
1

Storage & Compliance

Storage
-20.0°C
Research Use Only
Yes

Additional Specifications

Target
Phospho-Histone H3 (Thr6)
Reactivity
Human Vertebrates
Application
WB, ELISA, Luminex
MW(Calculated)
15kD
MW(Observed)
--
Host Species
Rabbit
Isotype
Rabbit IgG
Conjugate
Unconjugated
Modification
Phospho
Modification site
Thr6
Recommended dilution ratio
WB 0.1 ug/mL - 1 ug/mL; ELISA 0.2 ug/mL - 1 ug/mL; Luminex 0.1 ug/mL – 1 ug/mL.
Formulation
50% Glycerol/PBS with 1% BSA and 0.09% sodium azide
Source
--
Purification
Protein A affinity purified from an animal origin-free culture supernatant
Purity
--
Storage
-20.0°C
Concentration
1 mg/mL
Clonality
Recombinant Monoclonal
Clone Number
WR-225
Immunogen
A phospho-peptide corresponding to Phospho-Histone H3 (Thr6)
Sequence
--
Specificity
This antibody reacts to Histone H3 phosphorylated at Threonine 6. No cross reactivity with other phosphorylated histones
Gene name
--
Protein name
--
Alternative name
H3pT6
Organism-1
Human
Gene ID‑1
8350;8351;8352;8353;8354;8355;8356;8357;8358;8968
SwissProt-1
P68431;Q71DI3;P84243
Organism-2
Mouse
Gene ID‑2
319152;15077;15078
SwissProt-2
--
Organism-3
Rat
Gene ID‑3
291159;100361558
SwissProt-3
Q6LED0;P84245
Organism-4
--
Gene ID‑4
--
SwissProt-4
--
Cellular Localization
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Tech Support

ucallm

01

Documents

Datasheet, COA, SDS, and protocol files can be requested from technical support.

02

Storage & Handling

Storage
-20.0°C
03

Contact Support

Emailinfo@mail.ucallm.com

Phone+(1)-866-986-9598

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HoursMonday-Friday 09:00-18:00 CST

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Keywords:Histone Modification Antibodies