U-Blot® Histone H3 (Phospho pSer10) Rabbit mAb

U-Blot® Histone H3 (Phospho pSer10) Rabbit mAb
U-Blot® Histone H3 (Phospho pSer10) Rabbit mAb
$700.00
Size:100μL
SKU: WT8474-100

Catalog No.: WT8474

Specification: 100μL/300μL

Stock: In stock

Product details, specifications, documents, and related products are available from the catalog record. Learn more

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Product information

Product detailsSpecificationsQ & AEducation

Background: Histone serine phosphorylation is reversibly modulated by kinases and phosphatases. Phosphorylation alters chromatin charge and recruits functional proteins to regulate mitosis, transcription and DNA damage response, with distinct roles for each serine residue. H3 Ser10 phosphorylation (H3pS10) is a classic mitosis marker, strongly induced from G2 to M phase. It loosens compact chromatin to facilitate chromosome condensation and segregation. This modification also participates in gene transcriptional activation during interphase.

Product Overview

Catalog No.
WT8474
SKU
WT8474-100
Category
Histone Modification Antibodies
Product Type
Other
Size
100μL/300μL
Stock Status
In stock
Available Stock
20
Minimum Order Quantity
1

Storage & Compliance

Storage
-20.0°C
Research Use Only
Yes

Additional Specifications

Target
Phospho-Histone H3 (Ser10)
Reactivity
Human Vertebrates
Application
WB, ICC, ELISA, Luminex
MW(Calculated)
15kD
MW(Observed)
--
Host Species
Rabbit
Isotype
Rabbit IgG
Conjugate
Unconjugated
Modification
Phospho
Modification site
pSer10
Recommended dilution ratio
WB 0.5 ug/mL - 2 ug/mL; ICC 0.5 ug/mL - 2 ug/mL; ELISA 0.2 ug/mL - 1 ug/mL; Luminex 0.1 ug/mL – 1 ug/mL.
Formulation
50% Glycerol/PBS with 1% BSA and 0.09% sodium azide
Source
--
Purification
Protein A affinity purified from an animal origin-free culture supernatant
Purity
--
Storage
-20.0°C
Concentration
1 mg/mL
Clonality
Recombinant Monoclonal
Clone Number
WR-229
Immunogen
A phospho-peptide corresponding to Phospho-Histone H3 (Ser10)
Sequence
--
Specificity
This antibody reacts to Histone H3 phosphorylated at Serine 10. No cross reactivity with other phosphorylated histones.
Gene name
--
Protein name
--
Alternative name
H3pS10
Organism-1
Human
Gene ID‑1
8350;8351;8352;8353;8354;8355;8356;8357;8358;8968
SwissProt-1
P68431;Q71DI3;P84243
Organism-2
Mouse
Gene ID‑2
319152;15077;15078
SwissProt-2
--
Organism-3
Rat
Gene ID‑3
291159;100361558
SwissProt-3
Q6LED0;P84245
Organism-4
--
Gene ID‑4
--
SwissProt-4
--
Cellular Localization
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Tech Support

ucallm

01

Documents

Datasheet, COA, SDS, and protocol files can be requested from technical support.

02

Storage & Handling

Storage
-20.0°C
03

Contact Support

Emailinfo@mail.ucallm.com

Phone+(1)-866-986-9598

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Keywords:Histone Modification Antibodies