U-Blot® Histone H4 (Phospho Ser1) Rabbit mAb

U-Blot® Histone H4 (Phospho Ser1) Rabbit mAb
U-Blot® Histone H4 (Phospho Ser1) Rabbit mAb
$700.00
Size:100μL
SKU: WT8475-100

Catalog No.: WT8475

Specification: 100μL/300μL

Stock: In stock

Product details, specifications, documents, and related products are available from the catalog record. Learn more

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Product information

Product detailsSpecificationsQ & AEducation

Background: Histone serine phosphorylation is reversibly regulated by kinases and phosphatases. Phosphorylation changes chromatin charge and recruits functional proteins to control histone deposition, DNA repair and cell cycle, with unique functions for each site. H4 Ser1 phosphorylation (H4pS1) is a conserved N-terminal modification of newly synthesized histone H4 after DNA replication. It mediates nucleosome assembly and stabilizes chromatin structure. This modification accumulates at DNA double-strand break loci to relax chromatin and assist the recruitment of DNA repair complexes.

Product Overview

Catalog No.
WT8475
SKU
WT8475-100
Category
Histone Modification Antibodies
Product Type
Other
Size
100μL/300μL
Stock Status
In stock
Available Stock
20
Minimum Order Quantity
1

Storage & Compliance

Storage
-20.0°C
Research Use Only
Yes

Additional Specifications

Target
Phospho-Histone H4 (Ser1), H4S1p
Reactivity
Human Vertebrates
Application
WB, ICC, ELISA, Luminex
MW(Calculated)
11kD
MW(Observed)
--
Host Species
Rabbit
Isotype
Rabbit IgG
Conjugate
Unconjugated
Modification
Phospho
Modification site
Ser1
Recommended dilution ratio
WB 0.5 ug/mL - 2 ug/mL; ICC 1 μg/mL - 2 μg/mL; ELISA 0.2 ug/mL - 1 ug/mL; Luminex 0.1 ug/mL – 1 ug/mL.
Formulation
50% Glycerol/PBS with 1% BSA and 0.09% sodium azide
Source
--
Purification
Protein A affinity purified from an animal origin-free culture supernatant
Purity
--
Storage
-20.0°C
Concentration
1 mg/mL
Clonality
Recombinant Monoclonal
Clone Number
WR-230
Immunogen
A phospho-peptide corresponding to the Phospho-Histone H4 (pSer1).
Sequence
--
Specificity
This antibody reacts to Histone H4 phosphorylated at Serine 1. The reactivity is not affected by neighbor Arginine 3 modification. No cross reactivity with Histone H2A phosphorylated at Serine 1.
Gene name
--
Protein name
--
Alternative name
H4pS1
Organism-1
Human
Gene ID‑1
121504;554313;8294;8359;8360;8361;8362;8363;8364;8365;8366;8367;8368;8370
SwissProt-1
P62805
Organism-2
Mouse
Gene ID‑2
100041230
SwissProt-2
P62806
Organism-3
Rat
Gene ID‑3
100360950
SwissProt-3
P62804
Organism-4
--
Gene ID‑4
--
SwissProt-4
--
Cellular Localization
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Tech Support

ucallm

01

Documents

Datasheet, COA, SDS, and protocol files can be requested from technical support.

02

Storage & Handling

Storage
-20.0°C
03

Contact Support

Emailinfo@mail.ucallm.com

Phone+(1)-866-986-9598

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Keywords:Histone Modification Antibodies