U-Blot® Histone H2A/H4 (Phospho Ser1) Rabbit mAb

U-Blot® Histone H2A/H4 (Phospho Ser1) Rabbit mAb
U-Blot® Histone H2A/H4 (Phospho Ser1) Rabbit mAb
$700.00
Size:100μL
SKU: WT8476-100

Catalog No.: WT8476

Specification: 100μL/300μL

Stock: In stock

Product details, specifications, documents, and related products are available from the catalog record. Learn more

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Product information

Product detailsSpecificationsQ & AEducation

Background: Histone serine phosphorylation is a reversible modification regulated by kinases and phosphatases. Phosphorylation changes chromatin charge and recruits effector proteins to control chromatin assembly, DNA repair and cell cycle progression, with unique functions for each serine site. H2A Ser1 and H4 Ser1 phosphorylation are conserved N-terminal modifications. This mark is generated after DNA replication, participating in new histone deposition and nucleosome maturation. It also accumulates at DNA double-strand break sites to promote chromatin relaxation and repair factor recruitment.

Product Overview

Catalog No.
WT8476
SKU
WT8476-100
Category
Histone Modification Antibodies
Product Type
Other
Size
100μL/300μL
Stock Status
In stock
Available Stock
20
Minimum Order Quantity
1

Storage & Compliance

Storage
-20.0°C
Research Use Only
Yes

Additional Specifications

Target
Phospho-Histone H4 (Ser1), H2A/H4S1p
Reactivity
Human Vertebrates
Application
WB, ICC, ELISA, Luminex
MW(Calculated)
14kD, 11kD
MW(Observed)
--
Host Species
Rabbit
Isotype
Rabbit IgG
Conjugate
Unconjugated
Modification
Phospho
Modification site
Ser1
Recommended dilution ratio
WB 0.5 ug/mL - 2 ug/mL; ICC 1 μg/mL - 2 μg/mL; ELISA 0.2 ug/mL - 1 ug/mL; Luminex 0.1 ug/mL – 1 ug/mL.
Formulation
50% Glycerol/PBS with 1% BSA and 0.09% sodium azide
Source
--
Purification
Protein A affinity purified from an animal origin-free culture supernatant
Purity
--
Storage
-20.0°C
Concentration
1 mg/mL
Clonality
Recombinant Monoclonal
Clone Number
WR-228
Immunogen
An unmodified peptide corresponding to the N-terminus of Histone H3.
Sequence
--
Specificity
This antibody reacts to Histone H4 or Histone H2A phosphorylated at Serine 1. No cross reactivity with other phosphorylated Histones.
Gene name
--
Protein name
--
Alternative name
H2A pS1 / H4 pS1
Organism-1
Human
Gene ID‑1
83348359
SwissProt-1
P04908,P62805
Organism-2
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Gene ID‑2
--
SwissProt-2
--
Organism-3
--
Gene ID‑3
--
SwissProt-3
--
Organism-4
--
Gene ID‑4
--
SwissProt-4
--
Cellular Localization
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Tech Support

ucallm

01

Documents

Datasheet, COA, SDS, and protocol files can be requested from technical support.

02

Storage & Handling

Storage
-20.0°C
03

Contact Support

Emailinfo@mail.ucallm.com

Phone+(1)-866-986-9598

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Keywords:Histone Modification Antibodies