U-Blot® Histone H2AX Rabbit mAb

U-Blot® Histone H2AX Rabbit mAb
U-Blot® Histone H2AX Rabbit mAb
$700.00
Size:100μL
SKU: WT8485-100

Catalog No.: WT8485

Specification: 100μL/300μL

Stock: In stock

Product details, specifications, documents, and related products are available from the catalog record. Learn more

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Product information

Product detailsSpecificationsQ & AEducation

Background: Nucleosomes consist of H2A-H2B dimers and H3-H4 tetramers. Core histones and histone variants maintain chromatin structure, genome stability and transcriptional regulation. Total histone antibodies detect unmodified full-length histone proteins for loading control and chromatin normalization in WB, ChIP and IF. H2AX is a DNA damage responsive H2A variant abundant in mammalian cells. Upon DNA double-strand breaks, H2AX is rapidly phosphorylated to initiate DNA damage checkpoint and repair signaling.

Product Overview

Catalog No.
WT8485
SKU
WT8485-100
Category
Histone Modification Antibodies
Product Type
Other
Size
100μL/300μL
Stock Status
In stock
Available Stock
20
Minimum Order Quantity
1

Storage & Compliance

Storage
-20.0°C
Research Use Only
Yes

Additional Specifications

Target
Histone H2AX
Reactivity
All Vertebrates
Application
WB, ICC. ELISA, Luminex
MW(Calculated)
15kD
MW(Observed)
--
Host Species
Rabbit
Isotype
Rabbit IgG
Conjugate
Unconjugated
Modification
Unmodified
Modification site
--
Recommended dilution ratio
WB 0.5 ug/mL – 2 ug/mL; ICC 1 ug/mL - 2 ug/mL; ELISA 0.2 ug/mL - 1 ug/mL; Luminex 0.2 ug/mL – 1 ug/mL.
Formulation
50% Glycerol/PBS with 1% BSA and 0.09% sodium azide
Source
--
Purification
Protein A affinity purified from an animal origin-free culture supernatant
Purity
--
Storage
-20.0°C
Concentration
1 mg/mL
Clonality
Recombinant Monoclonal
Clone Number
WR-234
Immunogen
A peptide corresponding to the C-terminus of human Histone H2AX
Sequence
--
Specificity
This antibody reacts to Histone H2AX protein, independent of post-translational modifications. No cross reactivity with other histone proteins. .
Gene name
--
Protein name
--
Alternative name
H2AX, H2A.X, H2AFX
Organism-1
Human
Gene ID‑1
3014
SwissProt-1
P16104
Organism-2
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Gene ID‑2
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SwissProt-2
--
Organism-3
--
Gene ID‑3
--
SwissProt-3
--
Organism-4
--
Gene ID‑4
--
SwissProt-4
--
Cellular Localization
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Tech Support

ucallm

01

Documents

Datasheet, COA, SDS, and protocol files can be requested from technical support.

02

Storage & Handling

Storage
-20.0°C
03

Contact Support

Emailinfo@mail.ucallm.com

Phone+(1)-866-986-9598

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HoursMonday-Friday 09:00-18:00 CST

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Keywords:Histone Modification Antibodies