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Benzoylation
Introduction
Lysine benzoylation (Kbz) is a reversible aromatic lysine acylation modification. Using benzoyl‑CoA as its acyl donor, this marker accumulates mainly on histone tails within gene promoters to remodel chromatin and mediate transcriptional regulation.
Products Solutions
We provide antibody‑based detection and enrichment tools for lysine benzoylation analysis, including a MultiPTM Rabbit Monoclonal Antibody mix designed for improved recognition of Kbz‑modified proteins.
- Multiple antibody formats
- Multi‑epitope antibody composition
- Kbz motif enrichment
Product List
| Product Type | Product Name | Catalog No. |
|---|---|---|
| Rabbit pAb | PanBenzoyllysine Rabbit pAb | WT9036 |
| Rabbit mAb | PanBenzoyllysine Rabbit mAb | WT9037 |
| Mouse mAb | PanBenzoyllysine Mouse mAb | WT9175 |
| MultiPTM | Benzoyllysine MultiPTM Rabbit Monoclonal Antibody mix | WT9037M |
| Motif(BenzoylK) Kit | BenzoylLysine Motif (BenzoylK) Kit | WT919K |
Research Areas
- Epigenetic regulation
References
- Huang H, Zhang D, Wang Y, et al. Lysine benzoylation is a histone mark regulated by SIRT2. Nat Commun. 2018;9(1):3374. Published 2018 Aug 28.
- Li T, Chen J, Mi K, et al. Probiotics derived sodium benzoate improves social behavior of offspring exposed in the maternal immune activation through regulation of histone lysine benzoylation in astrocytes. Mol Psychiatry. 2025;30(12):5849‑5864.
- Wang D, Yan F, Wu P, et al. Global profiling of regulatory elements in the histone benzoylation pathway. Nat Commun. 2022;13(1):1369.