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Application SolutionsEpigenetic Enzyme Activity Research
Epigenetic modifications participate in cell fate determination, development and disease progression by regulating chromatin states and gene expression.
Application SolutionsKinase Activity and Inhibitor Screening
Protein kinases regulate cell proliferation, differentiation, metabolism, cell cycle and multiple signaling pathways via phosphorylation.
Application SolutionsProtein Interaction and Binding Studies
Build sensitive and high-throughput protein interaction assays, ranging from molecular interaction validation to drug screening.
Application SolutionsTR-FRET Technology
Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET) is a highly sensitive detection technology combining time-resolved fluorescence (TRF) and fluorescence resonance energy transfer (FRET).
Application SolutionsProtein‑macromolecule interaction
Protein-macromolecule interactions serve as the fundamental basis for cellular signal transduction, metabolic regulation, immune responses, and gene expression, with their dysregulation frequently associated with cancer, autoimmune diseases, and neurodegenerative disorders.
Application SolutionsSpatial/proximity interaction
Spatial/proximity interaction studies aim to capture the physical proximity between spatially adjacent molecules (protein-protein, protein-nucleic acid, protein-small molecule, etc.)
Application SolutionsProtein‑small molecule interaction
Protein-small molecule interactions constitute the molecular foundation of cellular life and drug discovery, participating extensively in enzymatic catalysis, signal transduction, metabolic regulation, and gene expression.
Application SolutionsProtein‑RNA interaction-Co-IP
RNA Immunoprecipitation (RIP) is a core molecular biology technique for studying intracellular RNA‑protein interactions, serving as a powerful tool for deciphering the dynamic processes of post‑transcriptional regulatory networks and revealing the functional roles of RNA‑binding proteins (RBPs).
Application SolutionsProtein-RNA interaction-Pull‑down
Protein-RNA interactions are central mechanisms of gene expression regulation, governing RNA processing, transport, translation, and degradation.
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