U-Blot® Rho A Mouse mAb(4E12)

Name: U-Blot® Rho A Mouse mAb(4E12)
SKU: WM1107
Availability: InStock

$268.00

Size:50μL

SKU: WM1107-50

Catalog No.: WM1107

Specification: 50μL/100μL

Stock: In stock

U-Blot® Rho A Mouse mAb(4E12) Learn more

Product details Specifications Q & A Education

Background：This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants have been identified. [provided by RefSeq, Sep 2015],

Product Overview

Catalog No.: WM1107
SKU: WM1107-50
Category: Mouse mAbs
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: Rho A
Reactivity: Human,Mouse,Rat
Application: IHC,WB
MW(Calculated): --
MW(Observed): 22kD
Host Species: Mouse
Isotype: --
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: IHC1:50-200;WB 1:1000-2000
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Monoclonal
Clone No.: 4E12
Immunogen: Synthesized peptide derived from human Rho A
Sequence: --
Specificity: This antibody detects endogenous levels of Rho A at Human, Mouse,Rat
Gene Name: RHOA ARH12 ARHA RHO12
Protein Name: Rho A
Other Name: Transforming protein RhoA;Rho cDNA clone 12;h12;
Organism-1: Human
Gene ID-1: 387
SwissProt-1: P61586
Organism-2: Mouse
Gene ID-2: 11848
SwissProt-2: Q9QUI0
Organism-3: Rat
Gene ID-3: 117273
SwissProt-3: P61589
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Cell membrane; Lipid-anchor; Cytoplasmic side. Cytoplasm, cytoskeleton. Cleavage furrow. Cytoplasm, cell cortex . Midbody. Cell projection, lamellipodium . Cell projection, dendrite . Nucleus . Localized to cell-cell contacts in calcium-treated keratinocytes (By similarity). Translocates to the equatorial region before furrow formation in a ECT2-dependent manner. Localizes to the equatorial cell cortex (at the site of the presumptive furrow) in early anaphase in an activated form and in a myosin- and actin-independent manner. .