U-Blot® GATA3 Rabbit pAb

U-Blot® GATA3 Rabbit pAb
U-Blot® GATA3 Rabbit pAb
$0.00
SKU: WP26789

Specification: 50µL/100µL

Stock: In stock

Product details, specifications, documents, and related products are available from the catalog record. Learn more

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Product information

Product detailsSpecificationsQ & AEducation

Background：This gene encodes a protein which belongs to the GATA family of transcription factors. The protein contains two GATA-type zinc fingers and is an important regulator of T-cell development and plays an important role in endothelial cell biology. Defects in this gene are the cause of hypoparathyroidism with sensorineural deafness and renal dysplasia. [provided by RefSeq, Nov 2009],

Product Overview

Catalog No.
WP26789
SKU
WP26789
Category
Polyclonal antibodies
Product Type
Other
Size
50µL/100µL
Stock Status
In stock
Available Stock
999
Minimum Order Quantity
1

Storage & Compliance

Research Use Only
Yes

Additional Specifications

Target
GATA 3
Reactivity
Human, Mouse
Applications
WB
MW(Calculated)
48kD
MW(Observed)
48kD
Host Species
Rabbit
Isotype
IgG
Conjugate/Modification
Unmodified
Recommended Dilution Ratio
WB 1:2000-1:10000
Formulation
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Purification
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Immunogen
--
Specificity
Endogenous
Gene Name
GATA3
Protein Name
Trans-acting T-cell-specific transcription factor GATA-3
Other Name
GATA3; / Trans-acting T-cell-specific transcription factor GATA-3; / GATA-binding factor 3
Species
Human
Gene ID
2625
Uniprot
P23771,
Species
Mouse
Gene ID
14462
Uniprot
P23772
Species
--
Gene ID
--
Uniprot
--
Cellular Localization
Nucleus.
Tissue Expression
T-cells and endothelial cells.
Signaling_pathway
Organismal Systems >> Immune system >> Th1 and Th2 cell differentiation;Organismal Systems >> Immune system >> Th17 cell differentiation;Human Diseases >> Immune disease >> Inflammatory bowel disease
Research Areas
>>Th1 and Th2 cell differentiation; / >>Th17 cell differentiation; / >>Parathyroid hormone synthesis, secretion and action; / >>Inflammatory bowel disease
Function
Disease:Defects in GATA3 are the cause of hypoparathyroidism with sensorineural deafness and renal dysplasia (HDR) [MIM:146255]; also known as Barakat syndrome.,Function:Transcriptional activator which binds to the enhancer of the T-cell receptor alpha and delta genes. Binds to the consensus sequence 5'-AGATAG-3'.,similarity:Contains 2 GATA-type zinc fingers.,tissue specificity:T-cells and endothelial cells.,

Tech Support

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Documents

Datasheet, COA, SDS, and protocol files can be requested from technical support.

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Keywords:Polyclonal antibodies