U-Blot® Wnt3a Rabbit pAb

U-Blot® Wnt3a Rabbit pAb
U-Blot® Wnt3a Rabbit pAb
$0.00
SKU: WP26792

Specification: 50µL/100µL

Stock: In stock

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Product information

Product detailsSpecificationsQ & AEducation

Background：The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 96% amino acid identity to mouse Wnt3A protein, and 84% to human WNT3 protein, another WNT gene product. This gene is clustered with WNT14 gene, another family member, in chromosome 1q42 region. [provided by RefSeq, Jul 2008],

Product Overview

Catalog No.
WP26792
SKU
WP26792
Category
Polyclonal antibodies
Product Type
Other
Size
50µL/100µL
Stock Status
In stock
Available Stock
999
Minimum Order Quantity
1

Storage & Compliance

Research Use Only
Yes

Additional Specifications

Target
Wnt3a
Reactivity
Human, Mouse, Rat
Applications
WB
MW(Calculated)
39kD
MW(Observed)
39kD
Host Species
Rabbit
Isotype
IgG
Conjugate/Modification
Unmodified
Recommended Dilution Ratio
WB 1:5000-1:20000
Formulation
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Purification
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Immunogen
--
Specificity
This antibody detects endogenous levels of Wnt3a and Wnt3.
Gene Name
wnt3a
Protein Name
--
Other Name
MGC119418; / MGC119419; / MGC119420; / Protein Wnt 3a Precursor; / Protein Wnt-3a; / Wingless type MMTV integration site family member 3A; / Wnt 3a; / wnt3a; / WNT3A protein; / WNT3A_HUMAN.
Species
Human
Gene ID
89780
Uniprot
P56704,
Species
Mouse
Gene ID
--
Uniprot
P27467
Species
--
Gene ID
--
Uniprot
--
Cellular Localization
Secreted, extracellular space, extracellular matrix . Secreted .
Tissue Expression
Moderately expressed in placenta and at low levels in adult lung, spleen, and prostate.
Signaling_pathway
Cellular Processes >> Cellular community - eukaryotes >> Signaling pathways regulating pluripotency of stem cells;Human Diseases >> Cancer: overview >> Pathways in cancer;Human Diseases >> Cancer: overview >> MicroRNAs in cancer;Human Diseases >> Cancer: specific types >> Hepatocellular carcinoma;Human Diseases >> Cancer: specific types >> Gastric cancer;Human Diseases >> Cancer: specific types >> Basal cell carcinoma;Human Diseases >> Cancer: specific types >> Breast cancer;Human Diseases >> Neurodegenerative disease >> Alzheimer disease;Human Diseases >> Neurodegenerative disease >> Pathways of neurodegeneration - multiple diseases;Environmental Information Processing >> Signal transduction >> Wnt signaling pathway;Environmental Information Processing >> Signal transduction >> Hippo signaling pathway;Environmental Information Processing >> Signal transduction >> mTOR signaling pathway
Research Areas
>>mTOR signaling pathway; / >>Wnt signaling pathway; / >>Hippo signaling pathway; / >>Signaling pathways regulating pluripotency of stem cells; / >>Melanogenesis; / >>Cushing syndrome; / >>Alzheimer disease; / >>Pathways of neurodegeneration - multiple diseases; / >>Human papillomavirus infection; / >>Pathways in cancer; / >>Proteoglycans in cancer; / >>MicroRNAs in cancer; / >>Basal cell carcinoma; / >>Breast cancer; / >>Hepatocellular carcinoma; / >>Gastric cancer
Function
Function:Ligand for members of the frizzled family of seven transmembrane receptors.,Function:Ligand for members of the frizzled family of seven transmembrane receptors. Wnt-3 and Wnt-3a play distinct roles in cell-cell signaling during morphogenesis of the developing neural tube.,similarity:Belongs to the Wnt family.,subunit:Interacts with PORCN.,tissue specificity:Moderately expressed in placenta and at low levels in adult lung, spleen, and prostate.,

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Keywords:Polyclonal antibodies