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Application SolutionsItaconate-Mediated Modifications
Itaconate is an immunometabolite that drives two distinct protein modifications: cysteine itaconation (S-itaconation) and lysine itaconylation (K-itaconylation).
Application SolutionsProtein Citrullination
Protein citrullination is an irreversible PTM that converts arginine residues to citrulline through peptidyl arginine deiminases (PADs).
Application SolutionsS-Nitrosylation
S-Nitrosylation involves the reversible attachment of nitric oxide (NO) to cysteine thiols, forming S-nitrosothiols (SNOs).
Application SolutionsCarboxyethylation
Carboxyethylation includes two distinct types of protein modifications with different mechanisms and biological functions.
Application SolutionsSerotonylation
Serotonylation is a recently characterized PTM, wherein serotonin is covalently conjugated to glutamine residues of substrate proteins.
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