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Application SolutionsGlutarylation
Lysine glutarylation (Kglu) is a reversible lysine acylation modification derived from glutaryl-CoA.
Application SolutionsLeucylation
Lysine leucylation (KLeu) represents a unique connection between amino acid metabolism and protein modification.
Application SolutionsFumarylation
Lysine fumarylation (Kfu) is a recently identified PTM first characterized in Escherichia coli.
Application SolutionsMethacrylation
Lysine methacrylation (Kmea) is a new type of posttranslational modification and a structural isomer of crotonyllysine (Kcr).
Application SolutionsItaconate-Mediated Modifications
Itaconate is an immunometabolite that drives two distinct protein modifications: cysteine itaconation (S-itaconation) and lysine itaconylation (K-itaconylation).
Application SolutionsProtein‑macromolecule interaction
Protein-macromolecule interactions serve as the fundamental basis for cellular signal transduction, metabolic regulation, immune responses, and gene expression, with their dysregulation frequently associated with cancer, autoimmune diseases, and neurodegenerative disorders.
Application SolutionsSpatial/proximity interaction
Spatial/proximity interaction studies aim to capture the physical proximity between spatially adjacent molecules (protein-protein, protein-nucleic acid, protein-small molecule, etc.)
Application SolutionsProtein‑small molecule interaction
Protein-small molecule interactions constitute the molecular foundation of cellular life and drug discovery, participating extensively in enzymatic catalysis, signal transduction, metabolic regulation, and gene expression.
Application SolutionsProtein‑RNA interaction-Co-IP
RNA Immunoprecipitation (RIP) is a core molecular biology technique for studying intracellular RNA‑protein interactions, serving as a powerful tool for deciphering the dynamic processes of post‑transcriptional regulatory networks and revealing the functional roles of RNA‑binding proteins (RBPs).
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