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Epithelial Stem Cells Derived from Pluripotent Stem Cells

Epithelial tissues are essential barrier and functional tissues in the human body, widely distributed in the skin, cornea, hair follicles, and the surfaces of various organs.

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Benzoylation

Lysine benzoylation (Kbz) is a reversible aromatic lysine acylation modification.

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2-Hydroxyisobutyrylation

Lysine 2-hydroxyisobutyrylation (Khib) is a widespread lysine acylation modification conserved across prokaryotic and eukaryotic organisms.

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S-Acylation (Commonly referred as S-palmitoylation)

Protein S-acylation is a reversible lipid modification involving the attachment of fatty acyl groups to cysteine residues through thioester bonds, with S-palmitoylation being its predominant form.

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Phosphorylation

Protein phosphorylation is one of the most abundant and extensively studied post-translational modifications (PTMs).

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Acetylation

Protein acetylation is a common post-translational modification (PTM) characterized by the addition of acetyl groups to lysine residues or protein N-termini.

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Glycosylation

Major forms of protein glycosylation include N-linked glycosylation and O-linked glycosylation, which differ in their attachment sites and biological functions.

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SUMOylation

SUMOylation is a reversible post-translational modification that regulates protein function through the covalent attachment of small ubiquitin-like modifier (SUMO) proteins to specific lysine residues in proteins.

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Ubiquitination

Ubiquitination is a dynamic protein modification that determines the fate and function of target proteins through the covalent attachment of ubiquitin molecules.

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