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Application SolutionsLeucylation
Lysine leucylation (KLeu) represents a unique connection between amino acid metabolism and protein modification.
Application SolutionsPyruvylation
Lysine pyruvylation (Kpy) is a metabolite-associated modification derived from pyruvate, a central intermediate of glycolysis.
Application SolutionsFumarylation
Lysine fumarylation (Kfu) is a recently identified PTM first characterized in Escherichia coli.
Application SolutionsMethacrylation
Lysine methacrylation (Kmea) is a new type of posttranslational modification and a structural isomer of crotonyllysine (Kcr).
Application SolutionsBenzoylation
Lysine benzoylation (Kbz) is a reversible aromatic lysine acylation modification.
Application SolutionsItaconate-Mediated Modifications
Itaconate is an immunometabolite that drives two distinct protein modifications: cysteine itaconation (S-itaconation) and lysine itaconylation (K-itaconylation).
Application SolutionsSerotonylation
Serotonylation is a recently characterized PTM, wherein serotonin is covalently conjugated to glutamine residues of substrate proteins.
Application SolutionsProtein Citrullination
Protein citrullination is an irreversible PTM that converts arginine residues to citrulline through peptidyl arginine deiminases (PADs).
Application SolutionsS-Nitrosylation
S-Nitrosylation involves the reversible attachment of nitric oxide (NO) to cysteine thiols, forming S-nitrosothiols (SNOs).
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