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Application SolutionsCuproptosis
Cuproptosis is a form of metal-dependent regulated cell death.
Application SolutionsFerroptosis
Ferroptosis is a form of regulated cell death driven by iron-dependent lipid peroxidation.
Application SolutionsLysozincrosis
Zinc ions (Zn²⁺) are essential trace elements that sustain normal cellular metabolism and physiological functions, yet aberrant zinc accumulation can trigger severe cytotoxicity.
Application SolutionsAlkaliptosis
Alkaliptosis is a novel form of regulated cell death driven by intracellular alkalinization, first proposed by Song et al. in pancreatic cancer research in 2018.
Application SolutionsCalcicoptosis
Calcicoptosis is a novel type of regulated cell death driven by disrupted intracellular calcium (Ca²⁺) homeostasis.
Application SolutionsNecrosis by sodium overload
Necrosis by sodium overload (NECSO) represents a novel metal/ion-dependent regulated cell death driven by disrupted intracellular Na⁺ homeostasis, which is characterized by osmotic collapse, energy exhaustion and secondary ionic toxicity triggered by aberrant sodium accumulation.
Application SolutionsMnoptosis
Mnoptosis is an emerging manganese-dependent regulated cell death modality triggered by disrupted intracellular Mn²⁺ homeostasis and abnormal Mn²⁺ accumulation.
Application SolutionsAD Signaling Pathway Research Solutions
Alzheimer’s disease (AD) is a complex neurodegenerative disorder driven by amyloid-β accumulation, tau pathology, neuroinflammation, synaptic dysfunction, and impaired cellular homeostasis.
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